The process of personality and behavioral change in humans faces serious challenges rooted in neural structures, lived experiences, and conscious interpretations. This article, with an interdisciplinary approach to neuroscience, psychology, and consciousness, seeks to clarify why humans resist change. The role of awareness (as the soul or inner observer) in selecting or validating brain patterns is also examined. From this perspective, change is possible, but it requires dismantling previous patterns, rebuilding neural networks, and passing through the anxiety caused by the threat to prior structures.
